Pharmaceutical Eye-Drop Filling Solution

LUNA's eye-drop solution integrates turntable feeding, peristaltic-pump filling, dropper (inner plug) inserting, outer-cap feeding, servo capping, labeling and collection in one compact, GMP-ready machine. Filling 5–100 ml at 30–40 BPM with ±1% dosing, the line achieves ≥99% yield on plug feeding, cap feeding and capping, with ±1 mm labeling accuracy. The peristaltic path keeps cleaning simple and minimizes cross-contamination — ideal for eye drops, liquid medicine and sensitive small-dose liquids. For higher-viscosity products, a rotary lobe-pump six-nozzle filler is available. ## Technical Specifications | Item | Range | |---|---| | Capacity | 3,000-24,000 vials/h | | Volume | 0.5-30 ml, accuracy ±1% | | Environment | Grade A laminar flow over Grade B (EU GMP) | | Filling | Peristaltic / ceramic pump, closed SUS or single-use path | | Compliance | EU GMP Annex 1, FDA 21 CFR Part 11 audit trail | ## Typical Line Configuration Bottle unscrambler, air shower, filling-plugging-capping monoblock under RABS/isolator, inline weight check, leak tester, labeler with serialization. ## Case Study An Indonesian pharma plant passed BPOM inspection with a 12,000 vials/h line featuring 100% inline weight verification. ## FAQ **Q: Does the line support both preserved and preservative-free formulations?** A: Yes. For preservative-free multi-dose, we integrate specialized dispensing closures; for unit-dose, BFS technology is offered as an alternative. **Q: What documentation is provided for validation?** A: Full DQ/IQ/OQ/PQ package, FAT/SAT protocols, material certificates and calibration records, aligned to GAMP 5. **Q: How is fill volume verified?** A: 100% inline gravimetric check with automatic reject and trend feedback to the filling pumps.